Meg Ryan, a beloved fixture of 1980s and '90s romantic comedies, has drawn public attention and medical scrutiny following a recent public appearance after a six-month hiatus.

The 61-year-old actress attended a New York screening of close friend Michael J. Fox's documentary on his Parkinson's disease battle, but it was her drastically altered appearance that has sparked widespread speculation about potential cosmetic procedures.

Top medical experts have evaluated photographs taken at the event and suggest multiple plastic surgeries may be responsible for the significant changes in Ryan's appearance. "The transformation is undeniable and frankly jarring," comments Chicago-based plastic surgeon Dr. Otto Placik. "While there don't seem to be any medical complications, her appearance seems less like a revitalized version of herself and more like a different person entirely."

Dr. Placik suggests that Ryan has undergone a series of surgeries, including a facelift that focused on her forehead, mid-face, upper and lower eyelids, and neck. Additionally, he suspects some sort of skin resurfacing procedure was done, resulting in her strikingly smooth and radiant complexion.

New York City plastic surgeon Dr. Joel Shahar concurs on the facelift speculation. He expresses concern over the unnatural results, stating, "The work done doesn't harmonize with her previous natural beauty. It's quite unusual and unfortunately, an indication of unsuccessful surgery."

Dr. Javad Sajan, a plastic surgeon based in Seattle, asserts that Ryan has endured a poorly executed eyelid procedure and an overly aggressive facelift. He specifically mentions the so-called "Joker Deformity," a surgical complication often cited among practitioners.

Despite these substantial changes, Ryan has continually denied having any cosmetic work done. In previous statements, she pointed out the ease with which others judge, saying, "It's so easy to judge." A representative for the actress recently reiterated this stance, dismissing rumors of extensive plastic surgeries as "completely fabricated."

It should be noted that the doctors quoted in this piece have not personally treated Meg Ryan.